产品名称：avivasysbio/RAF1 Protein Lysate (APL10391)/200ug/APL10391

产品编号：APL10391

市场价：¥4380.00

场地：美国(厂家直采)

产品分类：蛋白类>天然蛋白>球蛋白>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$219.00

品牌： avivasysbio

公司：avivasysbio

公司分类：

商品介绍

Additional Information:

Buffer Formulation: 0.1M Tris-HCl (pH 6.8) buffer containing 0.2M DTT, 4% SDS, 0.2% Bromophenol blue and 20% Sucrose.

Reconstitution and Storage:

Add 200ul of distilled water. Final concentration is 1 mg/ml. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.

Gene Symbol:

RAF1

Alias Symbols:

NS5, CRAF, Raf-1, c-Raf

NCBI Gene Id:

5894

Protein Name:

RAF proto-oncogene serine/threonine-protein kinase

Description of Target:

This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.

Swissprot Id:

P04049

Protein Accession #:

NP_002871

Nucleotide Accession #:

NM_002880

Molecular Weight:

Tissue Tool:

Find tissues and cell lines supported by DNA array analysis to express RAF1.

RNA Seq:

Find tissues and cell lines supported by RNA-seq analysis to express RAF1.

品牌介绍

avivasysbio英杰华系统生物学

关键目标家族和独特内容的抗体

我们丰富的抗体目录

Aviva Systems Biology为我们的客户提供了大量用于研究和诊断应用的高质量抗体。英杰华目前提供针对7,000多种不同蛋白质靶标的抗体，这是因为我们的高通量抗体生产每月会释放200多种新抗体。Aviva的重点是针对转录，表观遗传学和细胞信号传导领域关键靶标的抗体。Aviva的抗体库包含针对许多目标的独特抗体含量，这些目标是其他地方无法买到的。我们将重点放在面向家庭的抗体生产上，从而产生了针对大多数关键蛋白质家族成员的抗体，例如转录因子，转录调节剂，RNA结合蛋白，离子通道和细胞膜靶蛋白。