Predicted Species Reactivity:Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, ZebrafishProduct Format:Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.Clonality:PolyclonalHost:RabbitReconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.Gene Symbol:SMARCA5Official Gene Full Name:SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5NCBI Gene Id:8467Protein Name:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5Swissprot Id:O60264Protein Accession #:NP_003592Nucleotide Accession #:NM_003601Alias Symbols:ISWI, SNF2H, hISWI, hSNF2H, WCRF135, Description of Target:The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein.Protein Size (# AA):1,052Molecular Weight:122 kDaPurification:Affinity PurifiedTissue Tool:Find tissues and cell lines supported by DNA array analysis to express SMARCA5. RNA Seq:Find tissues and cell lines supported by RNA-seq analysis to express SMARCA5. Immunogen:The immunogen is a synthetic peptide directed towards the following sequence RFDWFLKSRTAMELQRRCNTLITLIERENMELEEKEKAEKKKRGPKPSTQPredicted Homology Based on Immunogen Sequence:Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 83%Complete computational species homology data:Anti-SMARCA5 (ARP30030_P050)Peptide Sequence:Synthetic peptide located within the following region: RFDWFLKSRTAMELQRRCNTLITLIERENMELEEKEKAEKKKRGPKPSTQConcentration:Batch dependent within range: 100 ul at 0.5 - 1 mg/mlProtein Interactions:SUMO2; SUMO3; HIST1H3A; UBC; RPA3; RPA2; RPA1; SUZ12; EED; RNF2; BMI1; HB-1; AT5G35210; LMNA; RSF1; BAZ1A; SMARCA5; WHSC1; SS18; SSX2; UL29; RNF168; VCP; NOTCH1; IK; HDAC2; HDAC1; CHRAC1; MBD3; PHGDH; NCSTN; POLR3A; RUVBL2; RBM14; SAP18; HNRNPR; EIF4A3; BBlocking Peptide:Available upon requestDatasheets/Manuals:Printable datasheet for anti-SMARCA5 (ARP30030_P050) antibody
avivasysbio英杰华系统生物学
关键目标家族和独特内容的抗体
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Aviva Systems Biology为我们的客户提供了大量用于研究和诊断应用的高质量抗体。英杰华目前提供针对7,000多种不同蛋白质靶标的抗体,这是因为我们的高通量抗体生产每月会释放200多种新抗体。Aviva的重点是针对转录,表观遗传学和细胞信号传导领域关键靶标的抗体。Aviva的抗体库包含针对许多目标的独特抗体含量,这些目标是其他地方无法买到的。我们将重点放在面向家庭的抗体生产上,从而产生了针对大多数关键蛋白质家族成员的抗体,例如转录因子,转录调节剂,RNA结合蛋白,离子通道和细胞膜靶蛋白。
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英杰华(Aviva)还拥有大量额外的17,000种抗体,这些抗体目前正在使用6个组织和6个细胞系进行全面的蛋白质印迹表征和验证。随着英杰华高通量处理团队对这些候选新产品的描述,我们预计明年将发布数千种新抗体产品。
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