产品名称：avivasysbio/UCP3 Antibody - middle region (ARP80687_P050)/100 ul/ARP80687_P050

产品编号：ARP80687_P050

市场价：¥5780.00

场地：美国(厂家直采)

产品分类：抗体类>二抗>抗仓鼠>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$289.00

品牌： avivasysbio

公司：avivasysbio

公司分类：

商品介绍

Tested Species Reactivity:

Human

Predicted Species Reactivity:

Human

Product Format:

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Clonality:

Polyclonal

Host:

Rabbit

Application:

Reconstitution and Storage:

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Gene Symbol:

UCP3

Official Gene Full Name:

uncoupling protein 3 (mitochondrial, proton carrier)

NCBI Gene Id:

7352

Protein Name:

mitochondrial uncoupling protein 3

Swissprot Id:

P55916-2

Protein Accession #:

NP_003347.1

Nucleotide Accession #:

NM_003356.3

Alias Symbols:

SLC25A9

Description of Target:

Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.

Protein Size (# AA):

275

Molecular Weight:

30 kDa

Purification:

Affinity purified

Tissue Tool:

Find tissues and cell lines supported by DNA array analysis to express UCP3.

RNA Seq:

Find tissues and cell lines supported by RNA-seq analysis to express UCP3.

Immunogen:

The immunogen is a synthetic peptide directed towards the middle region of human UCP3

Peptide Sequence:

Synthetic peptide located within the following region: CTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREE

Concentration:

Batch dependent within range: 100 ul at 0.5 - 1 mg/ml

Blocking Peptide:

For anti-UCP3 (ARP80687_P050) antibody is Catalog # AAP80687

Datasheets/Manuals:

Printable datasheet for anti-UCP3 (ARP80687_P050) antibody

品牌介绍

avivasysbio英杰华系统生物学

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Aviva Systems Biology为我们的客户提供了大量用于研究和诊断应用的高质量抗体。英杰华目前提供针对7,000多种不同蛋白质靶标的抗体，这是因为我们的高通量抗体生产每月会释放200多种新抗体。Aviva的重点是针对转录，表观遗传学和细胞信号传导领域关键靶标的抗体。Aviva的抗体库包含针对许多目标的独特抗体含量，这些目标是其他地方无法买到的。我们将重点放在面向家庭的抗体生产上，从而产生了针对大多数关键蛋白质家族成员的抗体，例如转录因子，转录调节剂，RNA结合蛋白，离子通道和细胞膜靶蛋白。