产品名称：avivasysbio/PAX5 Antibody - C-terminal region (ARP86926_P050)/ARP86926_P050/100 ul

产品编号：ARP86926_P050-100ul

市场价：¥5780.00

场地：美国(厂家直采)

产品分类：抗体类>二抗>抗小鼠>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$289.00

品牌： avivasysbio

公司：avivasysbio

公司分类：

商品介绍

Gene Symbol:

PAX5

Official Gene Full Name:

paired box 5

NCBI Gene Id:

5079

Protein Name:

paired box protein Pax-5

Swissprot Id:

Q02548-6

Protein Accession #:

NP_001267476.1

Nucleotide Accession #:

NM_001280547.1

Alias Symbols:

ALL3, BSAP

Description of Target:

This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms.

Protein Size (# AA):

357

Molecular Weight:

39 kDa

Host:

Rabbit

Clonality:

Polyclonal

Purification:

Affinity purified

Application:

Tissue Tool:

Find tissues and cell lines supported by DNA array analysis to express PAX5.

RNA Seq:

Find tissues and cell lines supported by RNA-seq analysis to express PAX5.

Immunogen:

The immunogen is a synthetic peptide directed towards the C terminal region of human PAX5

Predicted Species Reactivity:

Human

Tested Species Reactivity:

Human

Peptide Sequence:

Synthetic peptide located within the following region: PPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRFPNPGL

Product Format:

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution and Storage:

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Concentration:

Batch dependent within range: 100 ul at 0.5 - 1 mg/ml

Blocking Peptide:

For anti-PAX5 (ARP86926_P050) antibody is Catalog # AAP86926

Datasheets/Manuals:

Printable datasheet for anti-PAX5 (ARP86926_P050) antibody

品牌介绍

avivasysbio英杰华系统生物学

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