Predicted Species Reactivity | Human, Mouse, Rat |
---|---|
Product Format | Liquid |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Conjugation | Unconjugated |
Application | WB, IF |
Reconstitution and Storage | Store at -20C. Avoid repeated freeze/thaw cycles. |
Immunogen | A phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Tyr771 of human PLCG1 |
Purification | Affinity purified against immunogen |
Datasheets/Manuals | Printable datasheet for anti-PLCG1 (OAAN02920) |
Preservative | 0.02% Sodium Azide |
Target Post-Translational Modification | Phospho-Tyr771 |
Application Info | WB: 1:500 - 1:2,000. IF: 1:100 - 1:200 |
Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Gene Symbol | PLCG1 |
---|---|
Official Gene Full Name | phospholipase C gamma 1 |
Alias Symbols | PLC1, NCKAP3, PLC-II, PLC148, PLCgamma1, PLC1, NCKAP3, PLC-II, PLC148, PLCgamma1, phospholipase C gamma 1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, PLCG1 |
NCBI Gene Id | 5335 |
Protein Name | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 |
Description of Target | The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. |
Swissprot Id | P19174 |
Protein Accession # | NP_002651.2 |
Nucleotide Accession # | NM_002660.2 |
Molecular Weight | 155 kDa |
Tissue Tool | Find tissues and cell lines supported by DNA array analysis to express PLCG1. |
RNA Seq | Find tissues and cell lines supported by RNA-seq analysis to express PLCG1. |
See our General FAQ page.
What is the species homology for "PLCG1 Antibody (Phospho-Tyr771) (OAAN02920)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".
How long will it take to receive "PLCG1 Antibody (Phospho-Tyr771) (OAAN02920)"?
This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".
What buffer format is "PLCG1 Antibody (Phospho-Tyr771) (OAAN02920)" provided in?
This item is provided in "Liquid".Additional format options may be available. For more information please contact info@avivasysbio.com.
What are other names for "PLCG1 Antibody (Phospho-Tyr771) (OAAN02920)"?
This target may also be called "PLC1, NCKAP3, PLC-II, PLC148, PLCgamma1, PLC1, NCKAP3, PLC-II, PLC148, PLCgamma1, phospholipase C gamma 1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, PLCG1" in publications.
What is the shipping cost for "PLCG1 Antibody (Phospho-Tyr771) (OAAN02920)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
What is the guarantee for "PLCG1 Antibody (Phospho-Tyr771) (OAAN02920)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
Can I get bulk pricing for "PLCG1 Antibody (Phospho-Tyr771) (OAAN02920)"?
You can get bulk pricing for this item by going here.
What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "155 kDa".Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.
What protocols are available for "PLCG1 Antibody (Phospho-Tyr771) (OAAN02920)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
What are positive controls for "PLCG1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What are negative controls for "PLCG1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
What other proteins interact with "PLCG1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
What biological processes are associated with "PLCG1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
What cellular components are associated with "PLCG1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
What protein functions are associated with "PLCG1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
Aviva Systems Biology为我们的客户提供了大量用于研究和诊断应用的高质量抗体。英杰华目前提供针对7,000多种不同蛋白质靶标的抗体,这是因为我们的高通量抗体生产每月会释放200多种新抗体。Aviva的重点是针对转录,表观遗传学和细胞信号传导领域关键靶标的抗体。Aviva的抗体库包含针对许多目标的独特抗体含量,这些目标是其他地方无法买到的。我们将重点放在面向家庭的抗体生产上,从而产生了针对大多数关键蛋白质家族成员的抗体,例如转录因子,转录调节剂,RNA结合蛋白,离子通道和细胞膜靶蛋白。
英杰华(Aviva)还拥有大量额外的17,000种抗体,这些抗体目前正在使用6个组织和6个细胞系进行全面的蛋白质印迹表征和验证。随着英杰华高通量处理团队对这些候选新产品的描述,我们预计明年将发布数千种新抗体产品。
英杰华欢迎客户提出建议,并鼓励研究人员通过info@avivasysbio.com与我们联系,以寻求满足其研究要求的特定抗体。如果我们有满足您需求的抗体,但尚未发布,我们将齐心协力使您的目标在队列中前进,并在发布新抗体时提醒您有可用的新抗体。